Ezetimibe, Oxidized Low Density Lipoprotein, Lp (a), and Dyslipidemia
نویسندگان
چکیده
منابع مشابه
Impact of Oxidized Low Density Lipoprotein Cholesterol under Ezetimibe or Rosuvastatin Therapy on Endothelial Function
Results: At baseline, MDA-LDL was inversely correlated with FMD (r=-0.565, p<0.05). MDA-LDL and FMD were improved in both groups (MDA-LDL: E; pre 155.7±73.8mg/dl, post 120.6±46.4mg/dl, p<0.05, R; pre 148.7±48.2mg/dl, post 104.2±28.9mg/dl, p<0.05), (FMD: E; pre 4.9±3.1%, post 7.6±2.5%, p<0.05, R; pre 4.3±1.8%, post 7.6±3.0%, p<0.01). Although the improvement of LDL was better in rosuvastatin gro...
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The oxidative modification of low-density lipoprotein (LDL) has been implicated in the pathogenesis of atherosclerosis, although little is known as yet about the precise mechanism of oxidation in vivo. The studies presented here demonstrate that, in the absence of cells or transition metals, oxidized LDL can modify native LDL through co-incubation in vitro such as to increase its net negative c...
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ژورنال
عنوان ژورنال: Journal of Atherosclerosis and Thrombosis
سال: 2010
ISSN: 1880-3873,1340-3478
DOI: 10.5551/jat.5918